Aside from an apparently normal childhood, Ruiz made his debut as a performer at a very young age; he was often showcased on Cuban television as a child, singing typical children's songs.
During a Cabaret Tropicana tour in the Dominican Republic, Ruiz defected, leaving the group to join some friends in the United States.
In 1996, with the collaboration of famed Colombian songwriter Omar Estefano and of Ricardo Quijano, Ruiz released his fourth consecutive platinum album, named "Destino" ("Destiny").
In that year, Sony U.S. Latin, released a compilation called "Salsa de Titanes" which included Rey Ruiz' single "Piano" featuring famous pianist Paquito Hechavarría.
Ruiz collaborated with Brazilian singer José Augusto in this album, when the pair recorded a duet song, "Siempre Mía" ("Always Mine").
In 2004, he released the album Mi Tentacion ("My Temptation"), that included the top hit "Creo en el Amor" ("I Believe in Love"), which was nominated for "Best Tropical Song" at the Latin Grammy Awards.
On June 7, 2024, renowned salsa artist Rey Ruiz released his single "La Guerra Acaba," marking a significant return to the music scene.
This track showcases Ruiz's signature salsa rhythms, blending traditional elements with contemporary sounds to captivate both long-time fans and new listeners.