2DHJ, 2J59, 2YUY5758471435ENSG00000107863ENSMUSG00000036591Q5T5U3Q6DFV3NM_020824NM_001081364NM_001128084NP_001354380NP_001354381NP_001354382NP_001354383NP_001354384NP_001395251NP_001395252NP_001395253NP_001395254Rho GTPase activating protein 21 is a protein that in humans is encoded by the ARHGAP21 gene.

[5] ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).

There is little scientific literature on ARHGAP21, but recent reviews highlighted that it plays an important role in cytoskeletal processes in cancer, substance transport within the cell, and insulin secretion [6] This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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