Born in Albany, Georgia, Lockette played college football for the Fort Valley State Wildcats and was signed by the Seahawks as an undrafted free agent in 2011.

[2] Lockette attended Monroe Comprehensive High School in Albany, where he played football and ran track and field.

He signed a letter of intent to play football for the Auburn Tigers, but did not attend the university after a low SAT score.

[5] In 2010, for the Fort Valley State Wildcats football team, Lockette served as a wide receiver and a kickoff returner, and finished with 23 receptions for 262 yards and one touchdown.

Lockette won Super Bowl XLVIII with the Seahawks on February 2, 2014, where he had one catch for 19 yards in the 43–8 win over the Denver Broncos.

Seattle's offensive coordinator Darrell Bevell said afterwards in a post-game interview that Lockette "could have done a better job staying strong on the ball.

"[15] On March 9, 2015, the Seahawks stated they would not tender Lockette, thus making him an unrestricted free agent; however, he eventually re-signed.