Doyle volunteered for the expedition under Lieutenant Stephen Decatur, Jr., which entered the harbor of Tripoli and destroyed the captured U.S. frigate USS Philadelphia on 16 February 1804 during the First Barbary War.

She gave fire support to the landing forces on D-Day, 6 June, received on board 37 survivors of LCIs 93 and 487, and served on patrol until returning to Plymouth on 15 July for brief overhaul.

Sailing 1 August 1944 for Oran, Doyle departed from that port ten days later for the invasion of southern France, escorting a convoy to the assault area and patrolling to cover the landings.

She continued to support the invasion by escorting convoys from Naples and patrolling off Marseilles until 21 September when she sailed for the United States, arriving at New York 3 October for overhaul.

On 30 June 1950, five days after the North Koreans crossed the 38th parallel, Doyle headed west from San Diego to support United Nations operations in Korea.

On 15 September 1950, an attempt by 800 South Korean guerrillas to make a secret landing for a raid on the enemy's rear lines went awry when their LST broached and stranded.

She returned to the western Pacific between 2 February and 21 July 1953, visiting Midway, Guam, Kwajalein, and various ports in the Philippines, as well as serving as station ship at Hong Kong for five weeks.