[1] Grucza's research mainly focuses on genetic and environmental causes of addiction, as well as the health effects of alcohol consumption.
[2][3] He has also conducted research on long-term effects of tobacco control policies targeting youth purchases.
These studies were noted in the Institute of Medicine's 2015 report on the potential public health benefits of raising the tobacco purchase age to 21.
[8][9][10] In 2016, he led a study analyzing data from the National Survey on Drug Use and Health that found that the increase in marijuana use by American adults was less than that initially reported.
[12] Grucza has received the Walter G. Klopfer Award from the Society for Personality Assessment for distinguished contribution to the literature in personality assessment, and was named an Outstanding Public Health Transdisciplinary Scholar by Washington University's Institute for Public Health in 2012.