He was previously at the Wellcome Centre for Human Genetics and a Professor by Research at Oxford University.
He has worked on physical mapping with Hans Lehrach at Imperial Cancer Research Fund laboratories in London, where he developed a suite of software tools for the construction and validation of physical maps [1] In 1995 he moved to the Sanger Centre to work on DNA sequence assembly where he wrote software that automatically analysed sequencing trace data in order to edit DNA sequence assemblies.
In 2010 he stepped down to concentrate on his own research leading a group working on quantitative genetics in plants and mice.
[5] He developed the HAPPY software package [6] used for high-resolution QTL mapping which led to the identification of a quantitative trait gene underlying behavioral variation in mice.
With Dr Paula Kover, Bath University, he has developed a genetic reference panel in Arabidopsis thaliana[8]