While primarily a second baseman throughout his career, Weeks transitioned to left field in 2015 and played first base in his final season.

Born and raised in Altamonte Springs, Florida, Weeks attended Lake Brantley High School.

Weeks did not become a full-time player for the Brewers until June 2005, when he was recalled from the Triple-A Nashville Sounds, despite playing much of the 2005 season with a thumb injury.

These HR/SB number are consistent with his minor league totals (playing in 209 games) of 21 home runs and 24 stolen bases.

[5] In Game 1 of the 2008 NL Division Series, Weeks made a key error in the third inning that led to three unearned runs scored by the Phillies in Philadelphia's 3–1 victory.

[6] On February 3, 2009, Weeks and the Brewers reached a one-year deal worth $2.45 million, thereby avoiding salary arbitration.

[7] In early 2009, sabermetrician Bill James wrote in John Dewan's "The Fielding Bible Volume II," that Weeks should be moved to a position other than second base, as he had 44 defensive misplays that season.

The deal includes an option for a 5th year provided Weeks is an everyday player in 2013 and 2014, and could raise the total value of the contract to $50 million.

Advanced defensive metrics pegged him as a league-average defender at the keystone, and his WAR of 3.3 was good for 3rd in the National League.

[15] Despite a slow start in April and May 2012, Weeks rebounded beginning in June and posted typical power numbers, albeit with a dip in his on-base totals, which had been a hallmark of his value to that point.

[18] Weeks received sporadic playing time, and had a .167 batting average with three extra base hits in 95 plate appearances through early June.

[22] On February 3, 2017, Weeks signed a minor league contract with the Tampa Bay Rays that included an invitation to spring training.

[23] On April 2, 2017, the Tampa Bay Rays announced Weeks had made the opening day roster and would platoon at first base with Logan Morrison.

For the season, Weeks had a slash line of .216/.321/.340/ hitting 2 homeruns in 37 games (112 plate appearances) striking out 49 times.

His grandfather was an outfielder in the Negro leagues during the 1940s, and his sister Kaisha was an NCAA Regional Finalist at Southern University in track.