[1] She made her debut as a lead actress in 2002, in the Telugu film Nee Thodu Kavali.

Subsequently, she appeared in several successful films including Baghban (2003), Dhoom (2004), Garam Masala (2005), Kyon Ki (2005), Phir Hera Pheri (2006) and Golmaal: Fun Unlimited (2006).

[3] Sen made her debut as a lead actress in the Telugu movie Nee Thodu Kavali.

Sen also did a cameo in the 2006 film Dhoom 2, and she followed it with Johnny Gaddaar, alongside newcomer actor Neil Nitin Mukesh.

[6] Sen was a celebrity contestant in the ninth season of the Indian version of the reality TV show Big Brother, Bigg Boss.

In 2016, Sen participated in the dance celebrity reality show, Jhalak Dikhhla Jaa 9 as a wild card entrant but did not get selected.