The Río San Rodrigo is a stream in the state of Coahuila, Mexico, and is a tributary of the Rio Grande.

[4] In 1849 a group of Seminoles migrated from Indian Territory to Mexico to establish a military colony.

About five hundred Kickapoos from Missouri joined Wild Cat's group on the Rio Grande at Eagle Pass.

Wild Cat, representing the entire group, was assigned approximately 70,000 acres (28,000 ha), half at the headwaters of the Rio San Rodrigo and half at the headwaters of the Rio San Antonio.

The citizens of Remolino, nearby, were not pleased and complained to the provisional government in Coahuila, which issued a decree saying that other lands would be found upon which the Indians could be settled.