His studio experience include arranging and production with Babyface, Anderson Paak, Mary J. Blige, Dr. Dre, Christina Aguilera, Diddy, and many more.

In 2018, Lewis arranged, scored, and remained musical director for Christina Aguilera's sold-out Liberation Tour, played musical sidekick on the hit WNYC podcast "Late Night Whenever" with Michelle Buteau, which Time Magazine dubbed as one of the "Best Podcasts of 2018",[2] was a featured musician and composer in the Netflix original special "Bumping Mics" with Jeff Ross and Dave Attell, and arranged Christina Aguilera's performance for Dick Clark's "New Year's Rockin' Eve" which was viewed by more than eight million people.

[3] Lewis is also a co-writer of Anderson Paak's first single Tints, featuring Kendrick Lamar, from his album Oxnard, produced by Om'Mas Keith and Dr.

In 2021, Lewis founded 19 in the 4th Creative Collective to focus on developing talent and launching new music and visual projects, live performance platforms, and more.

Lewis was looked at as a child prodigy, simply because of how he applied his classical techniques on the Hammond Organ, and because he was teaching choirs at such a young age.

Lewis has produced, written songs, and arranged on several #1 albums including Christina Aguilera's Back to Basics,[6] Diddy's Press Play,[7] Fall Out Boy's Infinity on High,[8] Jamie Foxx's Unpredictable,[9] Herbie Hancock's "Possibilities", Heather Headley's Grammy Award winning "Audience of One", and Vanessa L. Williams' "The Real Thing".

[16] Along with arranging, he is also known for his scores and songs with film maker/playwright and NAACP Image Award winner David E. Talbert, who assigned him the moniker "Young Q", referring to Lewis as a "young Quincy Jones" (who Lewis always refers to as the "greatest musical role model" because of Jones' incredible wide range of abilities to arrange, compose, and produce music.)

For Talbert's feature film First Sunday, starring Ice Cube and Tracy Morgan, Lewis wrote and produced the song "Live Again" which played during the end credits.

In 2004, Lewis was contracted by Aguilera to arrange her Grammy performance of "Beautiful", which featured a 21-piece string orchestra, the Roger Wagner Chorale, and her band.

[21] In 2012, Lewis received vocal production and co-writing credits on her album "Lotus" (Sing For Me), and he remains her pianist, arranger, and musical director for all of her live performances today.

In 2006, Christina Aguilera brought Lewis into the studio to work with her to arrange and produce the vocals for music mogul Diddy's lead single "Tell Me".

Shrugging the notion off Lewis didn't give it much thought, until he received a call from MTV stating that Diddy wanted him to be a part of the series Making the Band.

As a vocal coach and producer, Lewis was featured on MTV's Making the Band, Season 3 with Diddy and pop girl group Danity Kane.

In 2017, Lewis was commissioned to create the musical arrangements for the Total Package Tour, with New Kids on the Block, Paula Abdul, and Boyz II Men.

Lewis was an on-air personality, dubbed the "One Man House Band", for the last three seasons of the VH1 television show Big Morning Buzz Live, when 98 Degrees frontman Nick Lachey became the host.

All residents at the shelter received brand new coats and accessories for Christmas from all over the world, through generous donations and support from NKOTB fans, affectionately known as "Blockheads".

"The Dreamers Movement",[30] is dedicated to providing awareness, care, and help to the less fortunate, using music and the patronage of his supporters to give hope and inspire the lives of homeless young adults.

While on the road with various artists, Rob Lewis creates live jam sessions, in which he raises money and sponsors shelters and food banks in selected cities.