[2][3][4] Playing college baseball for the Tulane Green Wave, Segedin was named a semifinalist for the Golden Spikes Award in 2010, his junior year.

[7] While playing for the Trenton Thunder of the Class AA Eastern League in 2013, Segedin injured his hip and underwent surgery to correct a femoral acetabular impingement.

[10] After the 2015 season, the Yankees traded Segedin and a player to be named later or cash to the Los Angeles Dodgers for Tyler Olson and Ronald Torreyes.

[20] Sedegin played for Team Italy in the 2017 World Baseball Classic Segedin was again assigned to Oklahoma City to begin the 2017 season.

[22] On May 26, it was revealed that he had suffered a wrist injury while rehabbing his foot and would require surgery, extending his stay on the disabled list.

[9] During the winter of 2015–16, Segedin began taking online courses from Indiana University to earn a Master of Business Administration.