Robert George Macpherson (January 28, 1866 – November 27, 1926) was a Canadian Liberal pharmacist and politician.

Born in Erin, Wellington county, Canada West, Robert George Macpherson's grandfather, Hugh Macpherson, was a native of Islay an island off the west coast of Scotland, who emigrated to Canada in 1858 with Robert George's father, Archibald.

Macpherson attended Arthur public school and complemented his education at Gait Collegiate Institute.

Gaining a comprehensive knowledge of that trade, he settled in New Westminster, British Columbia and worked there from 1888 to 1895.

In 1925 he attempted a return to the House, running in Vancouver South, but was defeated by the incumbent Leon Johnson Ladner.