It bequeathed £2500 to Boston, to upgrade the infrastructure with an aqueduct, relieve the city's poor, and fund the First Town-House, a grand public meeting place.
[3] In Boston, he worked as a tailor, and kept a shop on State Street, "living in apartments overhead, as was the custom in those times.
He served as town Selectman for several years; and as a representative to the Massachusetts General Court,[3] being appointed House Speaker in 1646.
Another memorial plaque, placed in 1925, honors Keayne in downtown Boston, on the corner of State and Washington Streets.
[12] Each year on the first Monday in June the Ancient and Honorable Artillery Company leads a procession to the gravesite, laying a wreath in Keayne's memory.