After playing college basketball for the Gonzaga Bulldogs, he was selected by the Los Angeles Lakers with the last overall pick in the second round of the 2012 NBA draft.

In his junior year, he led Handsworth Secondary School to the British Columbia Provincial Championship; he was named MVP of the title game after scoring 17 points, grabbing 12 rebounds, and blocking four shots.

[4] In that same year he was selected to play for the Canadian Junior National team at the 2005 Global Games and the 2006 World Championship qualifiers.

Sacre came back strong in the 2009–10 season, averaging 10.3 points, 5.4 rebounds, and 1.9 blocks per game as the Bulldogs' starting centre.

On January 8, 2013, Sacre made his first career start, finishing with 10 points, four blocked shots and three rebounds in a 125–112 loss to the Houston Rockets.

[18][19][20] On March 11, 2021, Sacre was announced as the assistant general manager for the Fraser Valley Bandits of the Canadian Elite Basketball League (CEBL).

He averaged 9 points, 8.2 rebounds, and 3 blocks per game at the 2006 FIBA Americas Under-18 Championship, helping the Canadians to a fourth-place finish in the tournament.

[22] Sacre was called to the senior national team for the first time to participate at the 2010 FIBA World Championship in Turkey.