[1] After graduation, he worked at Ernst & Young in Atlanta, Georgia, as a project lead before starting his own consulting firm, advising businesses from London to Singapore.

After leaving the private sector, he served as treasurer and auditor for the city, helping to improve its credit rating and lower debt service costs.

As a member of the General Assembly, he led efforts to combat the addiction crisis by working with law enforcement, community leaders, and doctors on preventing prescription drug abuse, reducing overdose deaths, and improving treatment systems.

[3][4] During the 130th General Assembly, Representative Sprague chaired a special committee that traveled the state gathering information on the opioid addiction crisis.

[5] Through legislation he sponsored and supported, he was deeply involved in addressing many addiction related issues, including: In the 131st General Assembly, Representative Sprague was chairman of the House Finance Subcommittee on Health and Human Services.

During his run for office, Sprague received endorsements from the editorial boards of the Columbus Dispatch, Cleveland Plain Dealer, Akron Beacon Journal, and several other Ohio publications.

[28] However, Sprague withdrew from the race on February 5, 2025, running instead for Ohio Secretary of State and endorsing Vivek Ramaswamy in the gubernatorial election.