[3] Doyne studied medicine in Oxford, Bristol and St George's Hospital in London.
In 1899 Doyne discovered colloid bodies lying on Bruch's membrane that appeared to merge, forming a mosaic pattern that resembled a honeycomb.
Today this condition is known to be a rare hereditary form of macular degeneration that results in progressive and irreversible loss of vision.
In 1889, he was the first physician to describe angioid streaks, a disorder that affects Bruch's membrane, the innermost layer of the choroid.
Two years after his death in 1916, a prized distinction in British ophthalmologic medicine known as the "Doyne Memorial Lecture" was established.