The stream flows to the southwest roughly parallel to I-44.
The stream confluence with Fivemile Creek is in Oklahoma at 36°58′51″N 94°37′27″W / 36.98083°N 94.62417°W / 36.98083; -94.62417 and just under one half mile west of the Missouri-Oklahoma border.
[2][1] Rock Branch was so named on account of the rocky character of its creek bed.
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