In 1906 he founded, along with Federico Gutierrez (an ex-police turned anarchist) the satirical newspaper La Mentira (The lie).
The activities of violent direct actions at times were supported and never condemned by Pacheco's newspaper while La Protesta had a different attitude, clearly opposed to the anarchist expropriators.
In this context, in 1926 was condemned to 6 months in prison for defending Kurt Wilckens, the instigator of what is known as the tragic Patagonia massacre.
He was a lecturer and activist in Argentina, Uruguay, Paraguay, Chile, Mexico, Cuba and Spain, a country to which he travelled during the Spanish Civil War of 1936.
On 3 June 1927 A Contramano was released and one year later El hombre de la plaza pública (The Man in the Public Square), both produced by Enrique Muiño.
In collaboration with Peter E. Picco, he wrote the piece Nace un pueblo (A village is born), Juan de Dios, milico y paisano and others.
Gonzalez Pacheco was one of the pioneers of Argentine cinematography, collaborating with Hugo Mac Dougall in producing Tres hombres del rio (Three men from the river) directed by Mario Soffici, which earned the Condor Academic Prize from the Academy of Arts and Cinematography Sciences of Argentina for the best original presentation in 1943.