Roger Lawson Gamble (1787 – December 20, 1847) was a United States representative and lawyer from Georgia.
He was elected to the U.S. House again as a Whig to represent Georgia in the 27th U.S. Congress and served one term from March 4, 1841, until March 3, 1843, as his lost his reelection bid for a second term in that seat in 1842.
From 1845 to 1847, Gamble served as a judge of the superior court of Georgia.
He died in Augusta, Georgia, on December 20, 1847, and was buried in Old Capitol Cemetery in Louisville.
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