[3] It traverses through several districts, providing irrigation to vast agricultural lands.

The canal's primary flow is towards the south, irrigating districts including Sukkur, Khairpur, Naushahro Feroze, Shaheed Benazirabad, Matiari, Hyderabad, Sanghar and Badin.

[4][5] It is a perennial canal, meaning it supplies water throughout the year.

The Rohri Canal is part of the larger Sukkur Barrage irrigation system.

While the Rohri Canal's construction was completed before the barrage project.