[1][2] Its cathedral, the Catedral Basílica de Santa Ana, is a minor basilica.

The cathedral is located in the city of (Santa Ana de) Coro, the capital of Falcón State, which has been designated a World Heritage Site ("Coro and its port La Vela").

Its ecclesiastical province comprises the metropolitan's own archdiocese and a single suffragan bishopric: On 21 June 1531, the first Diocese of Coro was established by Pope Clement VII, on territory split off from the then Diocese of Santo Domingo in the Dominican Republic.

The present Diocese of Coro was established by Pope Pius XI on 12 October 1922.

On 13 July 1997 it lost territory to establish its suffragan, the Diocese of Punto Fijo.