The diocese of Ifakara (in Latin: Dioecesis Ifakarensis) is a see of the Roman Catholic Church suffragan of the Roman Catholic Archdiocese of Dar-es-Salaam.

The diocese corresponds to the Kilombero District in the Morogoro Region in Tanzania.

Its see is located in the city of Ifakara, where the cathedral of Saint Patrick stands.

The diocese was created on January 14, 2012, by the Papal bull Nuper est petitum of Pope Benedict XVI, taking territories from the Roman Catholic Diocese of Mahenge.

At the date of its creation, the Diocese had a population of 322,779 people among whom 287,800 were baptized, which is 88.9%.