The Roman Catholic Diocese of Kenema (Latin: Kenemaën(sis)) is a diocese Catholic Church in the ecclesiastical province of Freetown in Sierra Leone.

The region that the Diocese comprises are the border from Bo District to the west, the Republic of Liberia in the southeast, Tonkolili District and Kono District in the north, Guinea in the east.

It was established on 11 November 1970, with its territory being split off from the diocese of Freetown and Bo.

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