On 16 May 2012 the Liberal Democratic Party of Russia decided to hand over to him a deputy mandate that became available after Aleksey Ostrovskiy received his position of Smolensk Oblast governor.

[2] He later sought re-election with the Rodina party but lost to United Russia candidate Alexander Zhupikov.

[5] On 21 December 2017, at the convention of the party Chestno (Honestly), Roman Khudyakov was nominated as a presidential candidate for the 2018 election.

[6] On 22 January 2018, Roman Khudyakov handed the collected signatures to the CEC, but immediately announced the withdrawal of his candidacy from the election and the support of the incumbent President Vladimir Putin.

[8][9] On 8 July 2014 Khudyakov declared that the image of Apollo driving Quadriga on the portico of the Bolshoi Theatre in Moscow on the 100-ruble banknote constitutes as pornography because the image shows Apollo's genitals and should only be available to people older than 18 years of age.