The amphitheatre is located in the ancient suburb of Neapolis, in what is now an archaeological park, near the Greek theatre and the Altar of Hieron.
The amphitheatre is on a different orientation to these other structures and probably follows the lines of an urban plan developed in the late classical period, which is reflected by the street discovered near the Sanctuary of Demeter in the suburb of Achradina.
The main road from Achradina to Neapolis led up to the amphitheatre through an Augustan period triumphal arch [it], whose foundations are still in situ.
[1] The amphitheatre is largely excavated out of the living rock and in the north east it takes advantage of the slope of the same rocky outcrop which the Greek theatre is built into.
[1] Four limestone fragments of a monumental inscription still survive from the amphitheatre, which most likely stood above the main entrance at the south end of the arena, according to Gentili.