In March 2021, Rosé released her debut single album R, which sold 448,089 copies in its first week, the highest figure by a Korean female soloist.

She is the second-most followed Korean individual on Instagram and appeared on Rolling Stone's list of living icons from Australia and New Zealand.

[13][14] She had initially presumed her father's idea was a joke due to the distance and difficulty of becoming a singer overseas saying that "she didn't think that there was much of a chance to become a K-pop star [herself].

[21] On 1 June 2020, it was announced that Rosé would debut as a solo artist following the release of Blackpink's first Korean language full-length album.

[22][23] On 30 December 2020, in an interview with South Korean media outlet Osen, her label revealed that filming for her debut music video would begin in mid-January 2021.

[34] In the United Kingdom, "On the Ground" became the first song by a female K-pop solo artist to enter the UK Singles Chart, with a debut at number 43.

U.S.[39] "Hard to Love", a pop-disco solo sung by Rosé, is featured as the fifth track of Blackpink's second studio album Born Pink, which was released on 16 September 2022.

[42] YG Entertainment subsequently confirmed on 29 December 2023 that Rosé and the other Blackpink members agreed not to proceed with a contract with the label for individual activities.

[47] She recorded a cover of Coldplay's 2008 song "Viva la Vida" for the trailer and finale of the Apple TV+ series Pachinko's second season in 2024.

[51][52] The song peaked at number two on the UK Singles Chart, marking the first time a female K-pop soloist reached the top ten.

[53] In the United States, it debuted at eight and peaked at number three on the US Billboard Hot 100, making Rosé the first female K-pop artist to enter the chart's top ten in history.

[60][61] Rosie debuted at number three on the Billboard 200,[62] for which she earned a Guinness World Record as the highest-charting female K-pop artist on the chart.

[70] After her solo debut with R, critic Kim Yoon-ha praises her memorable, husky tone that effectively conveys sorrow, aligning well with YG Entertainment's themes.

She said that Rosé's delicate yet powerful vocal style transforms superficial lyrics into something profound, enhancing her dynamic presence in Blackpink and her solo work.

[76] In December 2021, she announced her collaboration with the meditation and sleep app Calm, featuring her own bedtime story titled "Grounded With Rosé".

[77] In February 2022, alongside actor Yeo Jin-goo, Rosé was selected as one of the models for Korean retail store Homeplus for the brand's 25th anniversary promotions.

[82] In September 2021, Rosé attended the Met Gala, a fundraising event held annually at the Metropolitan Museum of Art Costume Institute in New York City, as Vaccarello's guest.

"[85] In March 2022, Rosé became the face of 2022 Tiffany HardWear campaign, having been photographed by Mario Sorrenti wearing a new necklace, bracelet, and full pavé diamond pieces.

[89] In September, Rosé, alongside footballer Kylian Mbappé and Formula One driver Lewis Hamilton, starred in Rimowa's 125th-anniversary campaign, "Never Still 4", as its latest global ambassador.

[90][91] In April 2024, she was featured in an editorial for Dazed Korea to launch Rimowa's Essential collection, consisting of travel accessories in its newest colours "Papaya" and "Mint".

[95][96] Continuing her work with Yves Saint Laurent, Rosé was chosen by Vaccarello to serve as a guest juror at the 2024 ANDAM Fashion Awards the same month.

[101] During the 2019–20 Australian bushfire season, Rosé posted on Instagram urging fans to support relief efforts, providing links to organisations that accepted donations and explaining, "We can make a difference if we all join in.

[102] For the 2023 Asia-Pacific Economic Cooperation (APEC) summit, Rosé spoke at a mental health awareness event in Cupertino hosted by United States First Lady Jill Biden.

In her speech, the singer opened up about her emotional struggles and the challenges that come with fame, and advocated for the prioritisation of mental health just as much as maintaining one's physical well-being.

[104] On 22 November 2023, she was invested into this Order by King Charles III, alongside the other group members of Blackpink during a special investiture at Buckingham Palace, which was also attended by President of South Korea Yoon Suk Yeol.

This allowed Rosé to successfully position herself "as an increasingly resonant global pop star from Korea", while "her linguistic and cultural fluency only strengthens her appeal.