Roseophilin is an antibiotic isolated from Streptomyces griseoviridis shown to have antitumor activity.

[1] The chemical structure can be considered in terms of two components, a macrotricyclic segment and a heterocyclic side-chain.

Several laboratory syntheses of roseophilin (e.g., those of Trost, Fürstner, Salamone) are based upon the Paal-Knorr synthesis, and two others are based on the Nazarov cyclization reaction (those of Tius, Frontier).

The compound is related to the prodiginines.

This systemic antibiotic-related article is a stub.