passing Moshav Bar Giora and Nes Harim Junction with Road 3866 where it turns eastward for 1.2 km.

At its lowest point of 550 meters, the road passes Jerusalem's largest sewage treatment facility (Sorek).

[2] It then begins a slow northeasterly ascent as it passes Jerusalem's main electrical substation (Sapir Station)[3] and the Sataf Spring Nature Reserve.

[4] Turning more easterly, it enters Jerusalem just before passing below Hadassah Hospital, intersecting with Route 395 at Kerem Junction.

The road passes Yad Vashem, the Mount Herzl National Cemetery and Sha'arei Tzedek Medical Center.