Roxburgh, Selkirk and Peebles was a county constituency of the House of Commons of the Parliament of the United Kingdom (Westminster) from 1955 to 1983.
The constituency was first defined by the First Periodical Review of the Boundary Commission, and first used in the 1955 general election, to cover the counties of Roxburgh, Selkirk and Peebles.
The boundaries of the Roxburgh, Selkirk and Peebles constituency were unaltered when the results of the Second Periodical Review were implemented for the February 1974 general election.
The Third Periodical Review took account of new local government boundaries, and results were implemented for the 1983 general election.
The Roxburgh and Berwickshire constituency, related to the Roxburgh and Berwickshire districts of the Borders region, and the Tweeddale, Ettrick and Lauderdale constituency, related to the Tweeddale and Ettrick and Lauderdale districts of the same region, were created.