[1] It moved to Commercial Road and opened there as the Royal Portsmouth, Portsea and Gosport Hospital in 1849.

[1] In the late 19th century it contained a 'Lock Ward' for the treatment of prostitutes under the regulations governed by the Contagious Diseases Acts 1863–1886.

If identified as a 'common prostitute' by the Metropolitan Water Police attached to the dockyard, women would be compulsorily examined and if found to be infected they would be detained until pronounced 'clean'.

[1] The former hospital was demolished and the site developed by Sainsbury's, who had a superstore there until its closure in 2021.

This site was part of a larger development known as the Northern Quarter, and incorporated the site of the demolished Tricorn Centre; that project was abandoned in 2016.