Ruby (Koyukon: Tl'aa'ologhe) is an incorporated town in central western Alaska, situated on the south bank of the Yukon River at the northwesternmost tip of the Nowitna National Wildlife Refuge.

A formerly sizeable gold-mining and lumbering town servicing the region, at the 2010 census the population was just 166, with only a general store and post office remaining as businesses,[3] down from 188 in 2000.

[citation needed] Gold was first discovered at the current townsite in 1906 on Ruby Creek.

In 1910 word leaked out about a gold strike on Long Creek, 30 miles south of Ruby, and a stampede was on.

Many of the men had left to fight in World War I, and several of the towns business people and their families were lost in the sinking of the Canadian passenger liner Sophia.

After World War II, Native Americans from near-by Kokrines relocated to Ruby to take advantage of the abandoned homes.

[5] According to the United States Census Bureau, the city has a total area of 7.6 square miles (20 km2).