The Rue de Nesle is a street in Saint-Germain-des-Prés in the 6th arrondissement of Paris, France.

It was formerly called the Rue d'Anjou Dauphine.

According to historians, an underground passage going to the Tour de Nesle existed at the no.

[1] It is home to the Museum of Letters and Manuscripts[2] and it crosses with the Rue Dauphine.

It is in short distance from the Seine and the Louvre Museum.