It serves Massachusetts Bay Transportation Authority (MBTA) rapid transit, bus, and commuter rail services and is located at the intersection of Ruggles and Tremont streets, where the Roxbury, Fenway–Kenmore, and Mission Hill neighborhoods meet.

A second phase is planned to add additional entrances to the Orange Line and commuter rail platforms.

The sprawling station is elevated above the Southwest Corridor north of Ruggles Street and west of Columbus Avenue - the former location of the South End Grounds.

The main station structure, designed by Stull and Lee, is covered by a rectangular "tubular-framed, high-tech" canopy.

Its open ends were intended to symbolize reconnection between Jamaica Plain and Roxbury, historically divided by the railroad alignment.

A Northeastern University architecture studio is located in the station structure under the upper busway, next to the Forsyth Street entrance.

[6] A total of five tracks run through the station: two for the Orange Line and three for commuter rail (and Amtrak, which does not stop).

The Orange Line tracks serve a single island platform on the north side of the railroad cut.

The work – part of a Northeastern University art program – depicts a woman blowing bubbles on a brightly colored backdrop.

[8][24] A preliminary study in 2008 recommended a full-length 800-foot platform located entirely east of the busway bridge.

[26] In December 2016, the MBTA Fiscal and Management Control Board approved a $1.6 million expansion of the project scope to include reconstruction of the lower busway, elevator replacements, additional station entrances, an additional busway elevator, and other accessibility improvements.

The Columbus Avenue entrance will be made accessible, with a covered ramp to the concourse and an improved pathway to the lower busway.

[41] Design reached 100% in August 2022; due to inflation and other factors, projected construction costs were $25 million higher than planned.