Count Palatine Rupert ruled as bishop elect of the Freising Hochstift from 1495 to 1498, without ever having been consecrated as a priest.

Rupert was adopted by his father-in-law and declared the heir of Bavaria-Landshut which led to the outbreak of the Landshut War of Succession after the death of Duke George in 1503.

After Elizabeth and Rupert were placed under the imperial ban by Emperor Maximilian on 23 April 1504, they died in quick succession later in 1504 of dysentery.

The war ended on 30 July 1505 with the arbitration of Emperor Maximilian I at the Cologne Reichstag.

The Duchy of Palatinate-Neuburg was created as a compensation for their surviving children Otto Henry and Philip.