She was the oldest of the children of the elector Frederick II of Saxony (1412–1464) from his marriage to Margaret (1416/7–1486), daughter of the Duke Ernest of Austria.

Amalia married on 21 March 1452 in Landshut Duke Louis IX of Bavaria-Landshut (1417–1479).

From the compensation for her Wittum, she received 800 Rhenish florins per year from her son.

Amalia acquired from her brothers and Rochlitz Castle and district, where she lived with a large entourage.

Here, she rebuilt the chapel in the castle and built St. Peter's Church in the town of Rochlitz.