She organized consumer support for the passage of the Federal Food, Drug, and Cosmetic Act of 1938, particularly targeting congressional wives and women's groups.

[5][6] In the Government building at the Fair, the FDA displayed seventeen boards showing "large, vivid pictures coupled with spare, terse prose".

[7] In October 1933, Paramount produced a 21⁄2 minute newsreel clip referencing the exhibit and discussing proposals for revised legislation, presented by Rexford Tugwell.

[8] Ruth Lamb used the nickname in the title of her book, American chamber of horrors: the truth about food and drugs (1936).

[7][9] Lamb's book was written in part to counter the criticisms of 100,000,000 Guinea Pigs: Dangers in Everyday Foods, Drugs, and Cosmetics (1933) by Arthur Kallet and Frederick J. Schlink.

Their book harshly criticized the FDA for not countering the marketing of dangerous and misleading foods, drugs and cosmetics.

Lamb "systematically explored the legal limitations" of the Wiley Act, explaining in detail areas where it was outdated, obsolete, or could not be applied, including the use of radio for advertising and the regulation of cosmetics and medical devices.

[7] Lamb also wrote a manuscript for The Devil's Candle: An Informal History of the Federal Food, Drug and Cosmetic Act and Its Operation in Our Social Economy (1937).

[2] She eventually returned to Washington, D. C., where she continued to work as a lobbyist for consumer groups such as the National Congress of Parents and Teachers (1942–45).