He finished his career playing 12 NFL games with two receptions and seven total yards gained.

The true freshman appeared in all 13 games as the Scarlet Knights enjoyed an 11–2 season in 2006 and won their first bowl championship.

Throughout his college career, D'Imperio recorded 177 total tackles, 6 quarterback sacks, and 2 interceptions, including one returned for a touchdown.

On September 3, 2011, D'Imperio was waived by the Vikings during final cuts before the start of the 2011 NFL season and added to the practice squad.

On August 31, 2012, D'Imperio was released during final roster cutdowns due to an injured shoulder.