During this term when cotton farmers were committing suicides across Telangana region, he brought a bottle of pesticide to the Legislative Assembly in order to bring to the notice of the highest house in the state.

One of the biggest influences in taking the movement of Telangana forward was when Hanmakonda legislator, Dasyam Vinay Bhaskar was forbidden to use the word Telangana on the floor of the Andhra Pradesh Legislative Assembly in 2000 when Telugu Desam was in power.

He started working with K. Chandrashekar Rao 10–12 months before the TRS party was formally launched in April 2001.

He won as an MLA in 2014 General elections from Bhupalapalle defeating former Chief Whip, Gandra Venkataramana Reddy.

Madhusudhana Chary has been nominated to Legislative Council under Governor's quota on 19 November 2021.