According to a news report issued by Hessenschau, the S2 is the least punctual of the system, with only 83% of trains leaving on time.

Between Frankfurt-Höchst and Central Station this service shares the Main-Lahn line with freight and shunting operations.

National and regional services use the parallel running Taunus railway in this section.

After the opening of the Frankfurt Citytunnel the service was renamed to S2 and extended to the new Hauptwache underground station.

Further extensions of the tunnel followed in 1983 (Konstablerwache) and 1990 (Ostendstraße and Lokalbahnhof) so that the Südbahnhof (South station) became the service's eastern terminal.