The S7 uses the former Aspangbahn right-of-way in the city center then, at Kledering, transitions to the former Pressburger Bahn, which connected Vienna and Bratislava, to Wolfsthal.

Average travel time between Floridsdorf and Vienna International Airport is 37 minutes.

The S7 uses the right of way of the former Aspang and Pressburger railways as well as the Vienna Trunk Line, in the city center.

After passing Kledering marshalling yard, the route briefly connects to the Danube Overland Railway, via Flying junction.

Past Wien Kaiserebersdorf, the route switches to the Pressburger railway, again via Flying Junction.