It offers 48 master's degree programs, 2 specialist degrees,[1] 17 post-baccalaureate and post-masters certificates,[2] doctoral programs in Education Administration and Nursing Practice, and three cooperative Doctor of Philosophy programs with SIU Carbondale.

[4] SIUE also has number of fellowship, grant, and award programs available to its graduate students.

[5] SIUE's Graduate Studies and Research ranks within the top 10 percent of its peer institutions in the U.S. receiving federal funding for research and development.

In FY 2011 the SIUE faculty and staff were awarded over $34 million from external federal and private agencies.

SIUE researchers are also responsible for developing innovative community outreach initiatives through and for the East St. Louis Center.