The submarine sank 13 ships in 15 patrols for a total of 10,040 gross register tons (GRT).

UB-19 was sunk in the English Channel at 49°56′N 2°45′W / 49.933°N 2.750°W / 49.933; -2.750 on 30 November 1916 by British Q ship HMS Penshurst (Q 7).

The submarine was powered by two Daimler six-cylinder four-stroke diesel engines each producing 284 metric horsepower (209 kW; 280 shp) (a total of 600 metric horsepower (440 kW; 590 shp)), two Siemens-Schuckert electric motors producing 280 metric horsepower (210 kW; 280 shp), and one propeller shaft.

She had a dive time of 32 seconds and was capable of operating at a depth of 50 metres (160 ft).

When submerged, she could operate for 45 nautical miles (83 km; 52 mi) at 5 knots (9.3 km/h; 5.8 mph); when surfaced she could travel 6,650 nautical miles (12,320 km; 7,650 mi) at 5 knots (9.3 km/h; 5.8 mph).