[3][4][5] Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds.

These cytosolic enzymes are different in their tissue distributions and substrate specificities.

The gene structure (number and length of exons) is similar among family members.

This gene encodes a phenol sulfotransferase with thermolabile enzyme activity.

Three alternatively spliced variants that encode the same protein have been described.