[5][6][7][8] This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma.

Recombination of these breakpoints results in the fusion of this gene and JAZF1.

The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.

The specific function of this gene has not yet been determined.

[8] SUZ12, as part of Polycomb Repressive Complex 2 (PRC2), may be involved with chromatin silencing in conjunction with HOTAIR ncRNA, using its zinc-finger domain to bind the RNA molecule.