8444774126ENSG00000162298ENSMUSG00000024807Q86TM6Q9DBY1NM_032431NM_172230NM_001164709NM_028769NP_115807NP_757385NP_001158181NP_083045E3 ubiquitin-protein ligase synoviolin is an enzyme that in humans is encoded by the SYVN1 gene.

[5][6] This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation.

The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER.

Sequence analysis identified two transcript variants that encode different isoforms.

[6] This article on a gene on human chromosome 11 is a stub.