High school and college education for boys moved in 1915 to Shawnee, to the facility that eventually became St. Gregory's University.

In October 1876, Father Isidore Robot completed a deal with the Potawotami Indians for a tribal grant of land which included the current site of Sacred Heart Mission.

[2] The Saint Mary's Academy was established in 1880 for the education of girls, along with a boarding school for boys, the Sacred Heart Institute.

A model farm - with a great variety of orchards, gardens, vineyards, fields, herds of animals and every form of agriculture was developed.

The farm had two main purposes: to supply food for the institution and to provide a model for the Indian boys to copy.

[2] On the night of January 15, 1901, a fire broke out in the dining room of the Indian Boys School and swept out of control.

Temporary wooden buildings were set up to carry on the boys' school, while the Sisters of Mercy moved one-quarter of a mile southeast to create a new St. Mary's Academy.

A large Tudor-Gothic structure, Benedictine Hall, was under construction there by 1913, opening its doors for high school and college students for its first term in 1915.

The church is an example of a restrained style of Gothic Revival, with a red tile roof and a stumpy front tower.