The Sacred Heart Cathedral (simplified Chinese: 徐州耶稣圣心主教座堂; traditional Chinese: 徐州耶穌聖心主教座堂) also known as the Cathedral of the Sacred Heart of Jesus, is a Roman Catholic cathedral in Xuzhou, China.

It is the seat of the Roman Catholic Diocese of Xuzhou.

The cathedral is located at 216 Youth Road.

[1] Construction of the Sacred Heart Cathedral, designed by German Catholic clergyman Joseph Wu, commenced in 1908 and was completed in 1910.

In April 1995, it has been designated as a provincial level cultural heritage conservation unit by the Jiangsu Provincial Government.