Sa'dun Hammadi (22 June 1930 – 14 March 2007; Arabic: سعدون حمادي) was an Iraqi politician and economist.

He rose to prominence after the seizure of power in Iraq by the Ba'ath Party and held numerous ministerial positions in the government.

He succeeded Saddam in 1991, who had previously been prime minister in addition to being president, but was forced out due to his reformist views and was made as the Speaker of the National Assembly in 1996 and continued to be in position until the 2003 invasion of Iraq.

In 1958, Gamal Abdel Nasser announced the formation of the United Arab Republic between Egypt and Syria.

He attended a leadership meeting that included Michel Aflaq, Salah al-Bitar, and Akram al-Hawrani.

During the 1991 Iraq rebellion Hammadi, a Shi'ite in the very top circle of the party, was appointed prime minister, likely due to placate Shi'ite Iraqi concerns over political dominance by a Sunni Arab clique from Tikrit.

In February 2004, after nine months in the custody of the Americans, he was released and subsequently resettled in Qatar while seeking medical treatment abroad He died in a German hospital from liver cancer on 14 March 2007.