Nicknamed the "Top Boxer of Bua Yai", he was known especially for his technical ability and is often regarded as one of the greatest fighters in the history of Muay Thai.

He was inspired to take up Muay Thai at the age of 11 after watching his older half-brother Kangwannoi Or.Sribualoi[1] fight out of the Sit Kru Od gym located in their hometown of Bua Yai.

Under the tutelage of Poompichai "Kru Od" Rattanavisid, he had his first fight after three months of training under the ring name of Klaisen Netsongkram.

Fighting between 66 and 77 lbs (30–35 kg), he rapidly became a recognized talent in Isan, the northeastern region of Thailand where he faced future champions such as Robert Kaennorasing and Samson Isaan.

Saenklai and Kangwannoi were 2 of the 4 fighters that first made the Sit Kru Od gym famous in Thailand.

During that year, Saenklai was considered to be one of the most successful Muay Thai fighters in the Kingdom of Thailand.

He was considered to be one of the most significant fighters in the 115 to 118 lbs (52.16–53.52 kg) weight divisions during the golden era of Muay Thai.

His victories against Veeraphol Sahaprom, Silapathai Jockygym, Taweesaklek Ploysakda, and Anantasak Panyuthaphum were considered his best fights.

[2] In the time leading up to his death, Saenklai almost died from tuberculosis but was saved by his doctor in Maharat Nakhon Ratchasima Hospital.