Qureshey currently serves as regent's professor at the University of California, Irvine's (UCI's) Graduate School of Management, and also actively supports U.C.

In 2000, he created the eponymous "Safi Qureshey Foundation" to provide "a conduit of support for socially and economically underserved children and adults to build better and more secure futures".

He later came to the United States and attended the University of Texas, Arlington, where he graduated with a BS in electrical engineering after transferring from the physics department.

[6] After leaving AST, Qureshey founded Quartics, an Irvine, California–based semiconductor startup developing systems-on-a-chip (SoC) for wireless video transmission.

[10] Qureshey was also a member of President Clinton's Export Council, where he traveled to emerging countries with successive Secretaries of Commerce to promote international business.

[11] Qureshey holds a number of patents related to web audio broadcasts and playback onto connected devices.

[1] He also provided funding for the Silicon Valley–based Koshish Foundation, a non-profit corporation focusing on education-related projects, to translate over 1,700 math and basic science videos to Urdu for e-learning company Khan Academy.